• Stichting IWO wordt bestuurd door artsen die werkzaam zijn in verschillende organisaties en specialismen, maar hetzelfde doel voor ogen hebben

  • Stichting IWO wordt bestuurd door artsen die werkzaam zijn in verschillende organisaties en specialismen, maar hetzelfde doel voor ogen hebben

Nieuws

Volg hier relevant internationaal nieuws over osteoporose. De nieuwsfeed bevat zowel doorgeplaatste artikelen, als publicaties uit de Osteoporose journalen. Klik hier voor rss-feeds.

 

  • Is There Enough Evidence to Use Bisphosphonates in HIV-Infected Patients? A Systematic Review and Meta-analysis.

    In conclusion, administration of oral and intravenous bisphosphonates was associated with increased bone mineral density at the lumbar spine and total hip over two years in HIV-positive patients. However, none of the... Lees meer

    Gepost op 19 October 2014

    Bron: http://www.medworm.com/inde....

  • When it Comes to Bone Health Males are the Weaker Sex

    Alarming new data published today by the International Osteoporosis Foundation (IOF), shows that one-third of all hip fractures worldwide occur in men, with mortality rates as high as 37% in the first year following... Lees meer

    Gepost op 19 October 2014

    Bron: http://www.medworm.com/inde....

  • Residual effect after oral bisphosphonate treatment and healthy adherer effects—the Swedish adherence register analysis (SARA)

    O. Strom et al. Osteoporosis International

    Little is known of the effect of alendronate and risedronate on osteoporotic fractures after discontinuation of therapy. We found that time on treatment was significantly... Lees meer

    Gepost op 19 October 2014

    Bron: http://www.medworm.com/inde....

  • Effects of long-term alendronate treatment on postmenopausal osteoporosis bone material properties

     N. Hassler et al. Osteoporosis International

    Raman microspectroscopic analysis of iliac crest from patients that were treated with alendronate (ALN) for 10 years revealed minimal, transient... Lees meer

    Gepost op 19 October 2014

    Bron: http://www.medworm.com/inde....

  • Effect of Oral Bisphosphonates for Osteoporosis on Development of Skeletal Metastases in Women With Breast Cancer: Results From a Pharmaco-epidemiological Study.

    J Natl Cancer Inst. 2014 Nov;106(11) Authors: Kremer R, Gagnon B, Meguerditchian AN, Nadeau L, Mayo N

    BACKGROUND: Treatment with bisphosphonates in women with breast cancer and established bone metastasis delays... Lees meer

    Gepost op 07 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • 'Unsung' cells double the benefits of a new osteoporosis drug

    Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns... Lees meer

    Gepost op 07 October 2014

    Bron: http://www.medworm.com/inde....

  • The Auckland calcium study: 5-year post-trial follow-up.

    Osteoporos Int. 2014 Jan;25(1):297-304 Authors: Radford LT, Bolland MJ, Mason B, Horne A, Gamble GD, Grey A, Reid IR

    INTRODUCTION: The Auckland calcium study was a 5-year randomised controlled trial of 1 g/day... Lees meer

    Gepost op 04 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures.

    Osteoporos Int. 2014 Jan;25(1):235-41 Authors: Johansson H, Odén A, McCloskey EV, Kanis JA

    INTRODUCTION: A prior vertebral fracture is a risk factor for future fracture that is commonly used as an... Lees meer

    Gepost op 04 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • An algorithm using the early changes in PINP to predict the future BMD response for patients treated with daily teriparatide.

    Osteoporos Int. 2014 Jan;25(1):377-84 Authors: Niimi R, Kono T, Nishihara A, Hasegawa M, Matsumine A, Nakamura T, Kono T, Sudo A

    INTRODUCTION: An algorithm using PINP is provided in osteoporotic patients with... Lees meer

    Gepost op 04 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Fracture prevention in patients with cognitive impairment presenting with a hip fracture: secondary analysis of data from the HORIZON Recurrent Fracture Trial.

    Osteoporos Int. 2014 Jan;25(1):77-83 Authors: Prieto-Alhambra D, Judge A, Arden NK, Cooper C, Lyles KW, Javaid MK

    INTRODUCTION: We tested whether the effects of zoledronic acid (Zol) on re-fracture and mortality... Lees meer

    Gepost op 04 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Switch patterns of osteoporosis medication and its impact on persistence among postmenopausal women in the UK General Practice Research Database

    Conclusion: Among women who switch their initial medication, even though switching to the second medication improves persistence during the initial therapy, persistence on the second and subsequent therapies remains... Lees meer

    Gepost op 04 October 2014

    Bron: http://www.medworm.com/inde....

  • Effect of Oral Bisphosphonates for Osteoporosis on Development of Skeletal Metastases in Women With Breast Cancer: Results From a Pharmaco-epidemiological Study

    Conclusion: Low-dose oral bisphosphonates administered for prevention or treatment of postmenopausal osteoporosis were associated with lower risk of skeletal metastasis in patients with early- or more advanced-stage breast... Lees meer

    Gepost op 04 October 2014

    Bron: http://www.medworm.com/inde....

  • There is Low Clinical Relevance of a Prevalent Vertebral Fracture in Old Men - the MrOs Sweden Study.

    Spine J. 2014 Sep 24; Authors: Kherad M, Rosengren BE, Hasserius R, Nilsson JA, Redlund-Johnell I, Ohlsson C, Ljunggren O, Lorentzon M, Mellström D, Karlsson MK 

    INTRODUCTION: The epidemiology, the... Lees meer

    Gepost op 01 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Managing osteoporosis with FRAX® in Australia: proposed new treatment thresholds from the 45&Up Study cohort.

    Bone. 2014 Sep 24; Authors: Chen JS, Simpson JM, Blyth FM, March LM 

    INTRODUCTION: Many people at high risk of fractures are not following traditional guidelines and not being recommended for intervention.... Lees meer

    Gepost op 01 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Timing of the initiation of bisphosphonates after surgery for fracture healing: a systematic review and meta-analysis of randomized controlled trials.

    Osteoporos Int. 2014 Sep 30; Authors: Li YT, Cai HF, Zhang ZL 

    We performed a systematic review and meta-analysis of randomized clinical trials. Early administration of bisphosphonates (BPs) after surgery did... Lees meer

    Gepost op 01 October 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • A cross-sectional study to examine the correlation between serum TSH levels and the osteoporosis of the lumbar spine in healthy women with normal thyroid function.

    Osteoporos Int. 2014 Sep 25; Authors: Noh HM, Park YS, Lee J, Lee W

    INTRODUCTION: We aimed to examine the association between serum thyroid-stimulating hormone (TSH) levels and osteoporosis of the lumbar spine in... Lees meer

    Gepost op 28 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • How to predict fragility fracture beyond ten years? The OFELY study.

    J Clin Endocrinol Metab. 2014 Sep 24;:jc20142601 Authors: Sornay-Rendu E, Duboeuf F, Boutroy S, Chapurlat R

    Context: Low bone mineral density (BMD) is a major determinant of fragility fractures (Fx) but its very... Lees meer

    Gepost op 28 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Predictors of re-fracture amongst patients managed within a secondary fracture prevention program: a 7-year prospective study

    Conclusions: Amongst patients managed within a dedicated SFP programme, poor compliance, multiple co-morbidities, corticosteroid therapy, low hip BMD or low body weight are all associated with increased risk of re-fracture.... Lees meer

    Gepost op 28 September 2014

    Bron: http://www.medworm.com/inde....

  • Distribution of vertebral fractures varies among patients according to hip fracture type

    Conclusion: The distribution of vertebral fractures among patients with subcapital fractures differed from the other fracture groups, which may indicate that subcapital fractures and some lumbar fractures have a different... Lees meer

    Gepost op 28 September 2014

    Bron: http://www.medworm.com/inde....

  • Ulnar fractures with bisphosphonate therapy: a systematic review of published case reports

    Conclusion: Ulnar fractures in patients with bisphosphonate therapy demonstrate features similar to those described for atypical femoral fractures, suggesting that these fractures could also possibly be due to... Lees meer

    Gepost op 28 September 2014

    Bron: http://www.medworm.com/inde....

  • Percutaneous vertebroplasty compared with conservative treatment in patients with chronic painful osteoporotic spinal fractures.

    J Clin Neurosci. 2014 Mar;21(3):473-7 Authors: Chen D, An ZQ, Song S, Tang JF, Qin H 

    The efficacy of percutaneous vertebroplasty (PVP) for patients with chronic painful osteoporotic compression fractures... Lees meer

    Gepost op 24 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Persistence at 12 months with denosumab in postmenopausal women with osteoporosis: interim results from a prospective observational study.

    Osteoporos Int. 2014 Sep 19; Authors: Silverman SL, Siris E, Kendler DL, Belazi D, Brown JP, Gold DT, Lewiecki EM, Papaioannou A, Simonelli C, Ferreira I, Balasubramanian A, Dakin P, Ho P, Siddhanti S, Stolshek B, Recknor... Lees meer

    Gepost op 24 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Proton-pump inhibitor use and hip fractures in men: a population-based case-control study.

    Ann Epidemiol. 2014 Apr;24(4):286-90 Authors: Adams AL, Black MH, Zhang JL, Shi JM, Jacobsen SJ

    PURPOSE: To estimate the association between proton-pump inhibitor (PPI) use and hip fracture. METHODS: We conducted a... Lees meer

    Gepost op 24 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Diagnosis and treatment of pediatric osteoporosis.

    Curr Opin Endocrinol Diabetes Obes. 2014 Sep 17; Authors: Bachrach LK 

    PURPOSE OF REVIEW: Progress toward identifying and treating disorders of bone fragility in pediatric patients has been considerable in... Lees meer

    Gepost op 20 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Glucocorticoids in Early Rheumatoid Arthritis: Are the Benefits of Joint-Sparing Effects Offset by the Adverse Effect of Osteoporosis? The Effects on Bone in the Utrecht Study and the CAMERA-II Study.

    Neuroimmunomodulation. 2014 Sep 12;22(1-2):66-71 Authors: Jacobs JW, Bijlsma JW, van Laar JM 

    This paper reviews the clinical effects on bone of 10 mg of prednisone daily in early rheumatoid arthritis, given... Lees meer

    Gepost op 20 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Healing of bisphosphonate-associated atypical femoral fractures in patients with osteoporosis: a comparison between treatment with and without teriparatide.

    J Bone Miner Metab. 2014 Sep 17; Authors: Miyakoshi N, Aizawa T, Sasaki S, Ando S, Maekawa S, Aonuma H, Tsuchie H, Sasaki H, Kasukawa Y, Shimada Y 

    Atypical femoral fracture (AFF) often appears with... Lees meer

    Gepost op 20 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Magnitude of fragility fracture risk in the very old-are we meeting their needs? The Newcastle 85+ Study.

    Osteoporos Int. 2014 Sep 16; Authors: Duncan R, Francis RM, Jagger C, Kingston A, McCloskey E, Collerton J, Robinson L, Kirkwood TB, Birrell F 

    INTRODUCTION: Fragility fractures are a major cause of excess... Lees meer

    Gepost op 18 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Merck Announces Data from Pivotal Phase 3 Fracture Outcomes Study for Odanacatib, an Investigational Oral, Once-Weekly Treatment for Osteoporosis

    Merck, known as MSD outside the United States and Canada, today announced data from the pivotal Phase 3 fracture outcomes study for odanacatib in postmenopausal women with osteoporosis. Odanacatib is Merck’s... Lees meer

    Gepost op 18 September 2014

    Bron: http://www.medworm.com/inde....

  • Relationship Between Pre-treatment Rate of Bone Loss and Bone Density Response to Once-Yearly ZOL: HORIZON-PFT Extension Study.

    J Bone Miner Res. 2014 Sep 11; Authors: Eastell R, Boonen S, Cosman F, Reid IR, Palermo L, Cummings SR, Black DM 

    Several studies have shown that high bone turnover is associated with 1) greater rates of bone... Lees meer

    Gepost op 14 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women.

    Vasc Health Risk Manag. 2014;10:533-8 Authors: Prasad M, Reriani M, Khosla S, Gössl M, Lennon R, Gulati R, Prasad A, Lerman LO, Lerman A 

    BACKGROUND: A growing body of evidence links coronary artery... Lees meer

    Gepost op 14 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Identifying Atypical Femoral Fractures-A Retrospective Review.

    Calcif Tissue Int. 2014 Sep 11; Authors: Juby AG, Crowther S, Cree M 

    Subtrochanteric atypical femoral fractures (AFFs) have been reported in patients on osteoporosis therapy (bisphosphonates and denosumab).... Lees meer

    Gepost op 14 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Comparative Effectiveness of Pharmacologic Treatments to Prevent Fractures: An Updated Systematic Review.

    Ann Intern Med. 2014 Sep 9; Authors: Crandall CJ, Newberry SJ, Diamant A, Lim YW, Gellad WF, Booth MJ, Motala A, Shekelle PG 

    Background: Osteoporosis is a major contributor to the propensity to fracture among... Lees meer

    Gepost op 12 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Goal-directed treatment of osteoporosis in Europe.

    Osteoporos Int. 2014 Sep 9; Authors: Kanis JA, McCloskey E, Branco J, Brandi ML, Dennison E, Devogelaer JP, Ferrari S, Kaufman JM, Papapoulos S, Reginster JY, Rizzoli R

    INTRODUCTION: Treat-to-target is a strategy... Lees meer

    Gepost op 12 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effect of simvastatin and atorvastatin on serum vitamin d and bone mineral density in hypercholesterolemic patients: a cross-sectional study.

    J Osteoporos. 2014;2014:468397 Authors: Thabit A, Alhifany A, Alsheikh R, Namnqani S, Al-Mohammadi A, Elmorsy S, Qari M, Ardawi M 

    Background. Besides lipid-lowering effect of statins, they have been shown to... Lees meer

    Gepost op 12 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density.

    J Bone Miner Res. 2014 Sep 5; Authors: Recker R, Benson C, Matsumoto T, Bolognese M, Robins D, Alam J, Chiang AY, Hu L, Krege JH, Sowa H, Mitlak B, Myers S 

    Sclerostin, a SOST protein secreted by osteocytes,... Lees meer

    Gepost op 12 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Are patterns of bone loss in anorexic and postmenopausal women similar? Preliminary results using high resolution peripheral computed tomography.

    Bone. 2014 Jan;58:146-50 Authors: Milos G, Häuselmann HJ, Krieg MA, Rüegsegger P, Gallo LM

    This study intended to compare bone density and architecture in three groups of women: young women with anorexia... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prevalent vertebral fractures on chest CT: higher risk for future hip fracture.

    J Bone Miner Res. 2014 Feb;29(2):392-8 Authors: Buckens CF, de Jong PA, Mali WP, Verhaar HJ, van der Graaf Y, Verkooijen HM 

    Subclinical or undiagnosed vertebral fractures on routine chest computed tomography... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Intravenous contrast injection significantly affects bone mineral density measured on CT.

    Eur Radiol. 2014 Sep 5; Authors: Pompe E, Willemink MJ, Dijkhuis GR, Verhaar HJ, Hoesein FA, de Jong PA

    OBJECTIVE: The objective is to evaluate the effect of intravenous contrast media on bone mineral density (BMD)... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Impact of Femoral Neck and Lumbar Spine BMD Discordances on FRAX Probabilities in Women: A Meta-analysis of International Cohorts.

    Calcif Tissue Int. 2014 Sep 4; Authors: Johansson H, Kanis JA, Odén A, Leslie WD, Fujiwara S, Glüer CC, Kroger H, Lacroix AZ, Lau E, Melton LJ, Eisman JA, O'Neill TW, Goltzman D, Reid DM, McCloskey... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Evaluation of the effect of selective serotonin reuptake inhibitors on bone mineral density: an observational cross-sectional study.

    Osteoporos Int. 2014 Sep 4; Authors: Ak E, Bulut SD, Bulut S, Akdağ HA, Oter GB, Kaya H, Kaya OB, Sengül CB, Kısa C

    Sixty patients diagnosed with generalized anxiety disorder and treated with either... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Clinician's Guide to Prevention and Treatment of Osteoporosis.

    Osteoporos Int. 2014 Aug 15; Authors: Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, Lindsay R

    The Clinician's Guide to Prevention and Treatment of Osteoporosis was developed by an expert... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Acute effect of zoledronic acid on the risk of cardiac dysrhythmias.

    Intern Emerg Med. 2014 Sep 5; Authors: Cipriani C, Castro C, Curione M, Piemonte S, Biamonte F, Savoriti C, Pepe J, De Lucia F, Clementelli C, Nieddu L, Minisola S 

    There have been recent concerns regarding... Lees meer

    Gepost op 06 September 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Oral Bone Drug Fails in Osteoporosis

    Postmenopausal women with osteoporosis treated with an oral calcium-sensing receptor antagonist showed increases in bone formation markers but it failed to boost bone mineral density (BMD) in a phase II dose-ranging study.... Lees meer

    Gepost op 06 September 2014

    Bron: http://news.google.com/news....

  • Osteoporosis is associated with antiepileptic drugs: a population-based study.

    Epileptic Disord. 2014 Aug 28; Authors: Wu FJ, Sheu SY, Lin HC

    Controversy remains regarding the risk of bone abnormalities due to enzyme-inducing antiepileptic drugs (EIAEDs) and non-enzyme-inducing antiepileptic... Lees meer

    Gepost op 31 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis.

    Int J Endocrinol. 2014;2014:235060 Authors: Locatelli V, Bianchi VE

    Background. Growth hormone (GH) and insulin-like growth factor (IGF-1) are fundamental in skeletal growth during puberty and bone health... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Do cadmium, lead, and aluminum in drinking water increase the risk of hip fractures? A NOREPOS study.

    Biol Trace Elem Res. 2014 Jan;157(1):14-23 Authors: Dahl C, Søgaard AJ, Tell GS, Flaten TP, Hongve D, Omsland TK, Holvik K, Meyer HE, Aamodt G, Norwegian Epidemiologic Osteoporosis Study (NOREPOS) Core Research... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Is vertebroplasty a risk factor for subsequent vertebral fracture, meta-analysis of published evidence?

    Osteoporos Int. 2014 Aug 23; Authors: Han SL, Wan SL, Li QT, Xu DT, Zang HM, Chen NJ, Chen LY, Zhang WP, Luan C, Yang F, Xu ZW

    INTRODUCTION: Vertebroplasty has been implicated in significant changes in vertebral... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • A Population-Based Nested Case-Control Study: The Use of 5-Alpha-Reductase Inhibitors and the Increased Risk of Osteoporosis Diagnosis in Patients With Benign Prostate Hyperplasia.

    Clin Endocrinol (Oxf). 2014 Aug 27; Authors: Lin WL, Hsieh YW, Lin CL, Sung FC, Wu CH, Kao CH

    BACKGROUND: 5-alpha-reductase inhibitors (5ARIs) are the potent androgen responsible for the development and enlargement... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Cortical Thickness of the Femur and Long-term Bisphosphonate Use.

    J Bone Miner Res. 2014 Aug 22; Authors: Niimi R, Kono T, Nishihara A, Hasegawa M, Matsumine A, Kono T, Sudo A

    Femoral cortical thickening has been mentioned in reports of atypical subtrochanteric/femoral shaft... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Bone Mineral Density Changes Among Women Initiating Proton Pump Inhibitors or H2 Receptor Antagonists: A SWAN Cohort Study.

    J Bone Miner Res. 2014 Aug 22; Authors: Solomon DH, Diem SJ, Ruppert K, Lian Y, Liu CC, Wohlfart A, Greendale GA, Finkelstein JS

    Proton pump inhibitors (PPIs) have been associated with diminished bone mineral... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • National Osteoporosis Society Vitamin D Guideline Summary

    The National Osteoporosis Society (NOS) published its document, Vitamin D and Bone Health: A Practical Clinical Guideline for Patient Management, in 2013 as a practical clinical guideline on the management of vitamin D... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.medworm.com/inde....

  • Increasing rates of pelvic fractures among older adults: The Netherlands, 1986-2011

    Conclusion: absolute numbers and incidence rates of pelvic fractures are increasing among the older Dutch population. Considering the fact the general population is growing older, an increasing number of elderly suffer from... Lees meer

    Gepost op 28 August 2014

    Bron: http://www.medworm.com/inde....

  • Balance training with multi-task exercises improves fall-related self-efficacy, gait, balance performance and physical function in older adults with osteoporosis: a randomized controlled trial.

    Clin Rehabil. 2014 Aug 20; Authors: Halvarsson A, Franzén E, Ståhle A

    OBJECTIVE: To evaluate the effects of a balance training program including dual- and multi-task exercises on fall-related... Lees meer

    Gepost op 24 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Genetics of osteoporosis.

    Biochem Biophys Res Commun. 2014 Aug 16; Authors: Urano T, Inoue S

    Osteoporosis is a skeletal disease characterized by low bone mineral density (BMD) and microarchitectural deterioration of bone tissue, which... Lees meer

    Gepost op 24 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Serum levels of 25-hydroxyvitamin D and the occurrence of musculoskeletal diseases: a 3-year follow-up to the road study.

    Osteoporos Int. 2014 Aug 20; Authors: Yoshimura N, Muraki S, Oka H, Nakamura K, Kawaguchi H, Tanaka S, Akune T 

    INTRODUCTION: The aim of this study is to clarify the association between serum 25-hydroxyvitamin... Lees meer

    Gepost op 24 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Heart failure: BMD a predictor of incident heart failure

    Nature Reviews Cardiology 11, 497 (2014). doi:10.1038/nrcardio.2014.108 Author: Tim Geach

    Heart failure is a known risk factor for osteoporosis. In a new paper, investigators now identify an independent association... Lees meer

    Gepost op 24 August 2014

    Bron: http://www.medworm.com/inde....

  • Duration of antiresorptive effects of low-dose zoledronate in osteopenic postmenopausal women: a randomized, placebo-controlled trial.

     J Bone Miner Res. 2014 Jan;29(1):166-72 Authors: Grey A, Bolland M, Mihov B, Wong S, Horne A, Gamble G, Reid IR 

    Annual intravenous administration of 5 mg zoledronate decreases fracture risk, but... Lees meer

    Gepost op 20 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effects of atorvastatin on bone mineral density (BMD) and bone metabolism in elderly males with osteopenia and mild dyslipidemia: A 1-year randomized trial.

    Arch Gerontol Geriatr. 2014 Jul 12; Authors: Chen ZG, Cai HJ, Jin X, Lu JH, Wang J, Fang NY 

    We explored the effects of atorvastatin on BMD and biochemical markers of bone metabolism in a 1-year, prospective,... Lees meer

    Gepost op 20 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Compromised peak bone mass in patients with inflammatory bowel disease--a prospective study.

    J Pediatr. 2014 Jun;164(6):1436-43.e1 Authors: Laakso S, Valta H, Verkasalo M, Toiviainen-Salo S, Mäkitie O 

    OBJECTIVE: To evaluate peak bone mass attainment in children and adolescents with inflammatory... Lees meer

    Gepost op 20 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Post-fracture pharmacotherapy for women with osteoporotic fracture: analysis of a managed care population in the USA.

    Osteoporos Int. 2014 Aug 12; Authors: Wilk A, Sajjan S, Modi A, Fan CP, Mavros P 

    INTRODUCTION: Pharmacologic therapy is recommended after osteoporotic fracture to reduce future fracture risk. The objective of... Lees meer

    Gepost op 17 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Use of FRAX as a Determinant for Risk-Based Osteoporosis Screening May Decrease Unnecessary Testing While Improving the Odds of Identifying Treatment Candidates.

    Womens Health Issues. 2014 Aug 12; Authors: Edwards FD, Grover ML, Cook CB, Chang YH 

    PURPOSE: We have assessed the hypothetical impact of guideline-concordant osteoporosis screening on baseline behaviors... Lees meer

    Gepost op 17 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Duration Of Breastfeeding As A Risk Factor For Vertebral Fractures.

    Bone. 2014 Aug 10; Authors: Bolzetta F, Veronese N, De Rui M, Berton L, Carraro S, Pizzato S, Girotti G, De Ronch I, Manzato E, Coin A, Sergi G 

    PURPOSE: Among the risk factors for osteoporosis and fractures,... Lees meer

    Gepost op 17 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Vitamin D insufficiency over 5 years is associated with increased fracture risk-an observational cohort study of elderly women.

    Osteoporos Int. 2014 Aug 13; Authors: Buchebner D, McGuigan F, Gerdhem P, Malm J, Ridderstråle M, Akesson K

    This study of elderly Swedish women investigated the association between chronic vitamin D... Lees meer

    Gepost op 17 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Cost-effectiveness of vitamin D and calcium supplementation in the treatment of elderly women and men with osteoporosis.

    Eur J Public Health. 2014 Aug 5; Authors: Hiligsmann M, Ben Sedrine W, Bruyère O, Evers SM, Rabenda V, Reginster JY 

    BACKGROUND: The supplementation with vitamin D and calcium has been recommended for... Lees meer

    Gepost op 12 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Fracture mortality: associations with epidemiology and osteoporosis treatment.

    Nat Rev Endocrinol. 2014 Aug 5; Authors: Sattui SE, Saag KG 

    The rates of incident osteoporotic fractures seem to be stabilizing; however, fragility fractures are still associated with considerable disability,... Lees meer

    Gepost op 12 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Osteoporosis in patients taking selective serotonin reuptake inhibitors: a focus on fracture outcome.

    Endocrine. 2014 Aug 5; Authors: Bruyère O, Reginster JY 

    Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs)... Lees meer

    Gepost op 12 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • A Frailty Index predicts 10-year fracture risk in adults age 25 years and older: results from the Canadian Multicentre Osteoporosis Study (CaMos).

    Osteoporos Int. 2014 Aug 8; Authors: Kennedy CC, Ioannidis G, Rockwood K, Thabane L, Adachi JD, Kirkland S, Pickard LE, Papaioannou A

    INTRODUCTION: In later life, frailty has been linked to fractures. It is likely... Lees meer

    Gepost op 12 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Comparison of the effect of 18-month daily teriparatide administration on patients with rheumatoid arthritis and postmenopausal osteoporosis patients.

    Osteoporos Int. 2014 Aug 1; Authors: Ebina K, Hashimoto J, Shi K, Kashii M, Hirao M, Yoshikawa H 

    INTRODUCTION: The aim of this study was to evaluate the effects of 18-month administration of daily... Lees meer

    Gepost op 05 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Patient perceptions of provider barriers to post-fracture secondary prevention.

    Osteoporos Int. 2014 Aug 1; Authors: Sale JE, Bogoch E, Hawker G, Gignac M, Beaton D, Jaglal S, Frankel L

    INTRODUCTION: Post-fracture secondary prevention programs have had modest effects on bone densitometry rates... Lees meer

    Gepost op 05 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).

    Maturitas. 2014 Jul 17; Authors: Rizzoli R, Stevenson JC, Bauer JM, van Loon LJ, Walrand S, Kanis JA, Cooper C, Brandi ML, Diez-Perez A, Reginster JY, for the ESCEO Task Force 

    From 50 years of age,... Lees meer

    Gepost op 05 August 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Risk factors for the second contralateral hip fracture in elderly patients: a systematic review and meta-analysis.

    CONCLUSIONS: Patients involved with female, living in institutions, osteoporosis, low vision, dizziness, dementia, respiration diseases and cardiac diseases were at risk for a second contralateral hip fracture after the... Lees meer

    Gepost op 01 August 2014

    Bron: http://www.medworm.com/inde....

  • Risk of atrial fibrillation with use of oral and intravenous bisphosphonates.

    Am J Cardiol. 2014 Jun 1;113(11):1815-21 Authors: Sharma A, Einstein AJ, Vallakati A, Arbab-Zadeh A, Walker MD, Mukherjee D, Homel P, Borer JS, Lichstein E 

    Clinical studies suggest an association between... Lees meer

    Gepost op 13 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Genome-wide Association Studies for Osteoporosis: A 2013 Update.

    J Bone Metab. 2014 May;21(2):99-116 Authors: Liu YJ, Zhang L, Papasian CJ, Deng HW 

    In the past few years, the bone field has witnessed great advances in genome-wide association studies (GWASs) of... Lees meer

    Gepost op 13 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The risk of major and any (non-hip) fragility fracture after hip fracture in the United Kingdom: 2000-2010.

    Osteoporos Int. 2014 Jul 8; Authors: Gibson-Smith D, Klop C, Elders PJ, Welsing PM, van Schoor N, Leufkens HG, Harvey NC, van Staa TP, de Vries F 

    The risk of a subsequent major or any fracture after a hip... Lees meer

    Gepost op 13 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • One-year disease-related health care costs of incident vertebral fractures in osteoporotic patients.

    Osteoporos Int. 2014 Jul 8; Authors: Lange A, Zeidler J, Braun S

    INTRODUCTION: OVCF are among the most common fractures related to osteoporosis. They have been shown to be associated with excess mortality and... Lees meer

    Gepost op 13 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Failure in the application of fragility fracture prevention guidelines.

    CONCLUSIONS: In conjunction with NICE and NOGG recommendations, FRAX(®) was able to identify 80% of our fracture population as intermediate or high risk on the day of fracture. Correct management was evident in a third... Lees meer

    Gepost op 13 July 2014

    Bron: http://www.medworm.com/inde....

  • Distinct effect of zoledronate and clodronate on circulating levels of DKK1 and sclerostin in women with postmenopausal osteoporosis.

    Bone. 2014 Jul 5; Authors: Gatti D, Viapiana O, Idolazzi L, Fracassi E, Ionescu C, Dartizio C, Troplini S, Kunnathully V, Adami S, Rossini M 

    The coupling of bone formation to bone resorption during treatment... Lees meer

    Gepost op 13 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Pleiotropic Effects of Obesity on Fracture Risk: The Study of Women's Health Across the Nation.

    J Bone Miner Res. 2014 Jul 1; Authors: Ishii S, Cauley JA, Greendale GA, Nielsen C, Karvonen-Gutierrez C, Ruppert K, Karlamangla AS

    Some aspects of an obese body habitus may protect against fracture risk (higher... Lees meer

    Gepost op 08 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Spine Bone Texture Assessed by Trabecular Bone Score (TBS) Predicts Osteoporotic Fractures in Men: The Manitoba Bone Density Program.

    Bone. 2014 Jul 1; Authors: Leslie WD, Aubry-Rozier B, Lix LM, Morin SN, Majumdar SR, Hans D

    INTRODUCTION:: One quarter of osteoporotic fractures occur in men. TBS, a gray-level measurement derived from lumbar spine... Lees meer

    Gepost op 08 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Efficacy and safety of odanacatib treatment for patients with osteoporosis: a meta-analysis.

    J Bone Miner Metab. 2014 Jul 5; Authors: Feng S, Luo Z, Liu D 

    The aim of this study was to evaluate the efficacy and safety of odanacatib (ODN) for the treatment of osteoporosis, using data in studies... Lees meer

    Gepost op 08 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Implications of expanding indications for drug treatment to prevent fracture in older men in United States: cross sectional and longitudinal analysis of prospective cohort study.

    BMJ. 2014;349:g4120 Authors: Ensrud KE, Taylor BC, Peters KW, Gourlay ML, Donaldson MG, Leslie WD, Blackwell TL, Fink HA, Orwoll ES, Schousboe J, Osteoporotic Fractures in Men (MrOS) Study Group 

    OBJECTIVES:... Lees meer

    Gepost op 08 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Improving Osteoporosis Management in General Practice: A Pharmacist-Led Drug Use Evaluation Program.

    Drugs Aging. 2014 Jul 4; Authors: Tan EC, George J, Stewart K, Elliott RA

    OBJECTIVE: The aim of the study was to evaluate the impact of a drug use evaluation (DUE) program on osteoporosis management in general... Lees meer

    Gepost op 08 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Does long-distance training saddle young cyclists with fragile bones?

    Young cyclists training to join the Tour de France could be causing irreversible damage.The combination of cycling extreme distances and restricting caloric intake to reduce weight can decrease bone density to levels that... Lees meer

    Gepost op 04 July 2014

    Bron: http://feeds.sciencedaily.c....

  • Osteoporosis and fractures in HIV/hepatitis C virus coinfection: a systematic review and meta-analysis.

    AIDS. 2014 Jun 28; Authors: Dong HV, Cortés YI, Shiau S, Yin MT 

    OBJECTIVE:: There is growing evidence that fracture risk is increased in individuals with HIV and/or hepatitis C virus (HCV) infection.... Lees meer

    Gepost op 04 July 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Incidence of subsequent vertebral body fractures after vertebroplasty.

    J Clin Neurosci. 2014 Jun 24; Authors: Zhang YZ, Kong LD, Cao JM, Ding WY, Shen Y

    The causal relationship between vertebroplasty and new-onset vertebral fractures remains unproved. We undertook a systematic review... Lees meer

    Gepost op 30 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Recovery from SIADH associated Osteoporosis - a case report.

    J Clin Endocrinol Metab. 2014 Jun 27;:jc20141572 Authors: Sejling AS, Thorsteinsson AL, Pedersen-Bjergaard U, Eiken P

    Introduction: Recent studies show an association between hyponatremia and osteoporosis. We have... Lees meer

    Gepost op 30 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Safety of denosumab in postmenopausal women with osteoporosis or low bone mineral density: a meta-analysis.

    Int J Clin Exp Pathol. 2014;7(5):2113-22 Authors: Zhou Z, Chen C, Zhang J, Ji X, Liu L, Zhang G, Cao X, Wang P 

    Purpose: The aim of this meta-analysis was to assess the safety of denosumab in postmenopausal... Lees meer

    Gepost op 30 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Describing variation in the delivery of secondary fracture prevention after hip fracture: an overview of 11 hospitals within one regional area in England.

    Osteoporos Int. 2014 Jun 26; Authors: Drew S, Sheard S, Chana J, Cooper C, Javaid MK, Judge A, The REFReSH study group

    INTRODUCTION: Hip fractures are usually the result of low impact falls and underlying... Lees meer

    Gepost op 30 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • A report from Fukushima: an assessment of bone health in an area affected by the Fukushima nuclear plant incident.

    J Bone Miner Metab. 2013 Nov;31(6):613-7 Authors: Ishii T, Ito K, Kato S, Tsubokura M, Ochi S, Iwamoto Y, Saito Y

    Bone health was assessed for inhabitants of an area affected by the Fukushima nuclear plant... Lees meer

    Gepost op 26 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Steroidal contraceptives: effect on bone fractures in women.

    Cochrane Database Syst Rev. 2014 Jun 24;6:CD006033 Authors: Lopez LM, Grimes DA, Schulz KF, Curtis KM, Chen M

    BACKGROUND: Steroidal contraceptive use has been associated with changes in bone mineral density in... Lees meer

    Gepost op 26 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The osteoporosis treatment gap.

    J Bone Miner Res. 2014 Jun 23; Authors: Kanis JA, Svedbom A, Harvey N, McCloskey EV

    Many guidelines for the assessment and treatment of osteoporosis recommend that intervention be considered in men and women who... Lees meer

    Gepost op 26 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • MicroRNA that blocks bone destruction could offer new therapeutic target for osteoporosis

    UT Southwestern cancer researchers have identified a promising molecule that blocks bone destruction and, therefore, could provide a potential therapeutic target for osteoporosis and bone metastases of cancer...

    Lees meer

    Gepost op 26 June 2014

    Bron: http://www.medworm.com/inde....

  • Mortality in British hip fracture patients, 2000 - 2010: a population-based retrospective cohort study.

    Bone. 2014 Jun 13; Authors: Klop C, Welsing PM, Cooper C, Harvey NC, Elders PJ, Bijlsma JW, Leufkens HG, de Vries F

    BACKGROUND: Data on recent trends in mortality after hip fracture are scarce. Aims were therefore... Lees meer

    Gepost op 20 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Serum Levels of Sclerostin and Dickkopf-1: Effects of Age, Gender and Fracture Status.

    Gerontology. 2014 Jun 12; Authors: Dovjak P, Dorfer S, Föger-Samwald U, Kudlacek S, Marculescu R, Pietschmann P

    Background: Fragility fractures, especially hip fractures, are a very common complication of... Lees meer

    Gepost op 20 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Long-term persistence and switching patterns among women using osteoporosis therapies: 24- and 36-month results from POSSIBLE US™

    Osteoporos Int. 2014 Jun 19; Authors: Wade SW, Satram-Hoang S, Stolshek BS

    Persistence with postmenopausal osteoporosis (PMO) medications is not well characterized beyond 12 months. Of 3,011 postmenopausal... Lees meer

    Gepost op 20 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Calcium Supplementation in Patients with Chronic Heart Failure: Is it Safe?

    Heart. 2014 Jun;100 Suppl 3:A31 Authors: Drozd M, Cubbon R, Gierula J, Jamil H, Crossfield S, Kearney M, Witte K

    INTRODUCTION: Recent observational studies have suggested that calcium supplementation in healthy... Lees meer

    Gepost op 15 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Fractures are increased and bisphosphonate use decreased in individuals with insulin-dependent diabetes: a 10 year cohort study.

    BMC Musculoskelet Disord. 2014 Jun 11;15(1):201 Authors: Fraser LA, Papaioannou A, Adachi JD, Ma J, Thabane L

    BACKGROUND: Individuals with diabetes have been found previously to be at increased risk of... Lees meer

    Gepost op 15 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Using a triggered endocrinology service consultation to improve the evaluation, management, and follow-up of osteoporosis in hip-fracture patients.

    Jt Comm J Qual Patient Saf. 2014 May;40(5):228-34 Authors: Hofflich HL, Oh DK, Choe CH, Clay B, Tibble C, Kulasa KM, Shah PK, Fink E, Girard PJ, Schwartz AK, Maynard GA

    BACKGROUND: Nearly 2 million... Lees meer

    Gepost op 15 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Time Course of Bone Mineral Density Changes With Denosumab Compared With Other Drugs in Postmenopausal Osteoporosis: A Dose-response Based Meta-analysis.

    Conclusion: This exploratory analysis shows that 3 years of treatment with denosumab resulted in bigger changes in LS and TH BMD compared with 3 years of treatment with 10 mg/day oral alendronate, 5 mg/year iv zoledronic... Lees meer

    Gepost op 15 June 2014

    Bron: http://www.medworm.com/inde....

  • Do bisphosphonates affect bone healing? A meta-analysis of randomized controlled trials.

    J Orthop Surg Res. 2014 Jun 5;9(1):45 Authors: Xue D, Li F, Chen G, Yan S, Pan Z

    BACKGROUND: Whether bisphosphonates affect indirect bone healing is still unclear. METHOD: We carried out a comprehensive search... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Patterns of treatment among a cohort of older low-income adults starting new medications for osteoporosis.

    Osteoporos Int. 2014 Jun 5; Authors: Solomon DH, Brown EM, Chandler D, Bower A, Barron R, Mogun H, Franklin JM

    INTRODUCTION: We described patterns and predictors of OP medication use, focusing on treatment changes... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Osteoporosis treatment disparities: a 6-year aggregate analysis from national survey data.

    Osteoporos Int. 2014 Jun 5; Authors: Cunningham TD, Di Pace BS, Ullal J

    We studied factors to determine the receipt of osteoporosis treatment in individuals with osteoporosis. Treatment was associated with age,... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prediction of Incident Hip Fracture with the Estimated Femoral Strength by Finite Element Analysis of DXA Scans in the Study of Osteoporotic Fractures.

    J Bone Miner Res. 2014 Jun 4; Authors: Yang L, Palermo L, Black DM, Eastell R

    A bone fractures only when loaded beyond its strength. The purpose of this study was to determine the association of femoral strength,... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Time Course of Bone Mineral Density Changes With Denosumab Compared With Other Drugs in Postmenopausal Osteoporosis: A Dose-response Based Meta-analysis.

    J Clin Endocrinol Metab. 2014 Jun 10;:jc20133795 Authors: Mandema JW, Zheng J, Libanati C, Perez Ruixo JJ

    Objective: Our objective was to compare the time course of bone mineral density (BMD) changes at the lumbar... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effect of TNF-alpha inhibitor treatment on bone mineral density in patients with ankylosing spondylitis: A systematic review and meta-analysis.

    Semin Arthritis Rheum. 2014 May 9; Authors: Nigil Haroon N, Sriganthan J, Al Ghanim N, Inman RD, Cheung AM

    OBJECTIVES: Ankylosing spondylitis (AS) is a chronic inflammatory disease associated with an increased risk... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Determinants associated with bone mineral density increase in response to daily teriparatide treatment in patients with osteoporosis.

    Bone. 2014 Jun 5; Authors: Niimi R, Kono T, Nishihara A, Hasegawa M, Matsumine A, Kono T, Sudo A

    INTRODUCTION: Several factors associated with bone mineral density (BMD) increase are reported with daily... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • New developments in biological markers of bone metabolism in osteoporosis.

    Bone. 2014 Jun 5; Authors: Garnero P

    Over the last 15years several biological markers of bone turnover have been developed with increased specificity and sensitivity. In osteoporosis clinical studies, the IOF and... Lees meer

    Gepost op 11 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The Combination of Vitamin D Deficiency and Mild to Moderate Chronic Kidney Disease Is Associated With Low Bone Mineral Density and Deteriorated Femoral Microarchitecture: Results From the KNHANES 2008-2011.

    J Clin Endocrinol Metab. 2014 May 30;:jc20133764 Authors: Lee YH, Kim JE, Roh YH, Choi HR, Rhee Y, Kang DR, Lim S

    Context: Although mild to moderate chronic kidney disease (CKD) and vitamin D deficiency are... Lees meer

    Gepost op 04 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Skeletal structure in postmenopausal women with osteopenia and fractures is characterized by abnormal trabecular plates and cortical thinning.

    J Bone Miner Res. 2014 May;29(5):1101-9 Authors: Stein EM, Kepley A, Walker M, Nickolas TL, Nishiyama K, Zhou B, Liu XS, McMahon DJ, Zhang C, Boutroy S, Cosman F, Nieves J, Guo XE, Shane

    The majority of fragility... Lees meer

    Gepost op 04 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Can change in FRAX score be used to "treat to target"? A population‐based cohort study.

    J Bone Miner Res. 2014 May;29(5):1074-80 Authors: Leslie WD, Majumdar SR, Lix LM, Morin SN, Johansson H, Odén A, McCloskey EV, Kanis JA

    It is unknown how responsive the Fracture Risk Assessment (FRAX) tool... Lees meer

    Gepost op 04 June 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The effect of oral contraceptive different patterns of use on circulating IGF-1 and bone mineral density in healthy premenopausal women.

    Endocrine. 2014 May 27; Authors: Elkazaz AY, Salama K 

    Both insulin-like growth factor-1(IGF-1) and oral contraceptive (OC) use have been linked to premenopausal breast and colorectal cancers, osteoporosis and... Lees meer

    Gepost op 30 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Multimorbidity in women with and without osteoporosis: results from a large US retrospective cohort study 2004-2009.

    Osteoporos Int. 2014 May 24; Authors: O'Malley CD, Tran N, Zapalowski C, Daizadeh N, Olenginski TP, Cauley JA 

    INTRODUCTION: This retrospective cohort study describes the incidence of an array of... Lees meer

    Gepost op 30 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Bone metabolism and adipokines: are there perspectives for bone diseases drug discovery?

    Expert Opin Drug Discov. 2014 May 24;:1-13 Authors: Scotece M, Conde J, Abella V, López V, Pino J, Lago F, Gómez-Reino JJ, Gualillo O

    Introduction: Over the past 20 years, the idea that white adipose... Lees meer

    Gepost op 30 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Adherence and efficacy of screening for low bone mineral density among ulcerative colitis patients treated with corticosteroids.

    Am J Gastroenterol. 2014 Apr;109(4):572-8 Authors: Khan N, Abbas AM, Almukhtar RM, Cole EB, Khan AN

    OBJECTIVES: Ulcerative colitis (UC) is associated with an increased risk of metabolic bone disease and fragility... Lees meer

    Gepost op 30 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • What analytic method should clinicians use to derive spine T-scores and predict incident fractures in men? Results from the MrOS study.

    Osteoporos Int. 2014 May 22; Authors: Hansen KE, Blank RD, Palermo L, Fink HA, Orwoll ES, for the Osteoporotic Fractures in Men (MrOS) Study Research Group

    INTRODUCTION: Spine T-scores have limited ability to... Lees meer

    Gepost op 25 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • External validity of a population-based study on osteoporosis and fracture.

    Acta Orthop. 2014 May 21;:1-5 Authors: Wihlborg A, Akesson K, Gerdhem P

    Background and purpose - Little is known about the characteristics of non-participants in epidemiological studies. We evaluated external... Lees meer

    Gepost op 25 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Estimating prevalence of osteoporosis: examples from industrialized countries.

    Arch Osteoporos. 2014 Dec;9(1):182 Authors: Wade SW, Strader C, Fitzpatrick LA, Anthony MS, O'Malley CD

    PURPOSE: Standardized country-specific prevalence estimates are scarce, limiting our ability to anticipate... Lees meer

    Gepost op 25 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Evaluation of fracture risk and potential drug holidays for postmenopausal women on long-term bisphosphonate therapy.

    Int J Womens Health. 2014;6:423-8 Authors: Kostoff MD, Saseen JJ, Borgelt LM 

    STUDY OBJECTIVE: To describe characteristics of postmenopausal women on long-term bisphosphonate therapy who fall into one of four... Lees meer

    Gepost op 25 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women.

    Endocrine. 2014 May 23; Authors: Yamauchi M, Yamaguchi T, Nawata K, Tanaka KI, Takaoka S, Sugimoto T

    Although a high serum low-density lipoprotein cholesterol (LDL-C) level is an established risk factor for... Lees meer

    Gepost op 25 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • NCCN Bone Health Task Force: Key Recommendations.

    J Natl Compr Canc Netw. 2014 May;12(5 Suppl):813-6 Authors: Farooki A 

    For patients with advanced cancers involving bone, the standard of care for maintaining bone health is the use of antiresorptive therapies... Lees meer

    Gepost op 25 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Vitamin D supplementation and lipid profile: What does the best available evidence show?

    Atherosclerosis. 2014 Apr 30;235(1):130-139 Authors: Challoumas D

    Vitamin D supplements have increasingly been used for the treatment and prevention of osteoporosis. Historically, effects of the vitamin on the... Lees meer

    Gepost op 21 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Vitamin k2 therapy for postmenopausal osteoporosis.

    Nutrients. 2014;6(5):1971-80 Authors: Iwamoto J

    Vitamin K may play an important role in the prevention of fractures in postmenopausal women with osteoporosis. Menatetrenone is the brand name of a synthetic vitamin... Lees meer

    Gepost op 21 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Subgroup Variations in Bone Mineral Density Response to Zoledronic Acid Following Hip Fracture.

    J Bone Miner Res. 2014 May 16; Authors: Magaziner JS, Orwig DL, Lyles KW, Nordsletten L, Boonen S, Adachi JD, Recknor C, Colón-Emeric CS, Mesenbrink P, Bucci-Rechtweg C, Su G, Johnson R, Pieper CF 

    ... Lees meer

    Gepost op 21 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Secondary osteoporosis and metabolic bone disease in patients 50 years and older with osteoporosis or with a recent clinical fracture: a clinical perspective.

    Curr Opin Rheumatol. 2014 May 17; Authors: Bours SP, van den Bergh JP, van Geel TA, Geusens PP

    PURPOSE OF REVIEW: The purpose of this review is to provide guidance to clinicians about which laboratory tests should... Lees meer

    Gepost op 21 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Medication Use Before and After Hip Fracture: A Population-Based Cohort and Case-Control Study.

    Drugs Aging. 2014 May 14; Authors: Rossini M, Viapiana O, Adami S, Idolazzi L, Buda S, Veronesi C, Degli Esposti L, Gatti D 

    BACKGROUND: Osteoporosis, together with age, is the main risk factor for hip... Lees meer

    Gepost op 18 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Estimated Lean Mass and Fat Mass Differentially Affect Femoral Bone Density and Strength Index But Are Not FRAX Independent Risk Factors for Fracture.

    J Bone Miner Res. 2014 May 13; Authors: Leslie WD, Orwoll ES, Nielson CM, Morin SN, Majumdar SR, Johansson H, Odén A, McCloskey EV, Kanis JA 

    Although increasing body weight has been regarded as... Lees meer

    Gepost op 18 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effect of Odanacatib on BMD and Fractures: Estimates from Bayesian Univariate and Bivariate Meta-analyses.

    J Clin Endocrinol Metab. 2014 May 13;:jc20141162 Authors: Gajic-Veljanoski O, Tomlinson G, Srighanthan J, Adachi JD, Josse R, Brown JP, Cheung AM

    Context: Odanacatib (ODN), a selective cathepsin-K inhibitor, was... Lees meer

    Gepost op 18 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Increase in bone density in patients with spondyloarthritis during anti-tumor necrosis factor therapy: 6-year followup study.

    J Rheumatol. 2013 Oct;40(10):1712-8 Authors: Durnez A, Paternotte S, Fechtenbaum J, Landewé RB, Dougados M, Roux C, Briot K

    OBJECTIVE: To assess the effects on bone mineral... Lees meer

    Gepost op 18 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Are young women and men with rheumatoid arthritis at risk for fragility fractures? A population-based study.

    J Rheumatol. 2013 Oct;40(10):1669-76 Authors: Amin S, Gabriel SE, Achenbach SJ, Atkinson EJ, Melton LJ

    OBJECTIVE: Older women and men with rheumatoid arthritis (RA) are at increased risk for fractures, but limited... Lees meer

    Gepost op 18 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effects of walking on the preservation of bone mineral density in perimenopausal and postmenopausal women: a systematic review and meta-analysis.

    Menopause. 2013 Nov;20(11):1216-26 Authors: Ma D, Wu L, He Z 

    OBJECTIVE: This study aims to critically evaluate the effects of a walking intervention on bone mineral density (BMD) in perimenopausal and... Lees meer

    Gepost op 14 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Calcium supplements not associated with increased risk of cardiovascular disease in women

    Calcium supplements are widely taken by women for bone health. Previous studies have suggested that calcium supplements may increase risk of cardiovascular disease, but the data has been inconsistent. A new study did not... Lees meer

    Gepost op 14 May 2014

    Bron: http://feeds.sciencedaily.c....

  • The Association between Aortic Calcification and Fracture Risk in Postmenopausal Women in China: The Prospective Chongqing Osteoporosis Study.

    PLoS One. 2014;9(5):e93882 Authors: Zhou R, Zhou H, Cui M, Chen L, Xu J 

    PURPOSE: Fractures are associated with cardiovascular diseases in the elderly. The purpose of the present study was to investigate the... Lees meer

    Gepost op 14 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Insulinogenic sucrose+amino acid mixture ingestion immediately after resistance exercise has an anabolic effect on bone compared with non-insulinogenic fructose+amino acid mixture in growing rats.

    Bone. 2014 May 8; Authors: Notomi T, Karasaki I, Okazaki Y, Okimoto N, Kato Y, Ohura K, Noda M, Nakamura T, Suzuki M

    Maximizing peak bone mass is an important factor in osteoporosis prevention. Resistance exercise... Lees meer

    Gepost op 14 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Osteoporosis and Fractures After Solid Organ Transplantation: A Nationwide Population-Based Cohort Study.

    Mayo Clin Proc. 2014 May 5; Authors: Yu TM, Lin CL, Chang SN, Sung FC, Huang ST, Kao CH 

    OBJECTIVE: To investigate the incidence of bone disorders after solid organ transplantation (SOT). PARTICIPANTS AND... Lees meer

    Gepost op 11 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Whole body bone tissue and cardiovascular risk in rheumatoid arthritis.

    J Osteoporos. 2014;2014:465987 Authors: Popescu C, Bojincă V, Opriş D, Ionescu R

    Introduction. Atherosclerosis and osteoporosis share an age-independent bidirectional correlation. Rheumatoid arthritis (RA)... Lees meer

    Gepost op 11 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Teriparatide Therapy for Denosumab-Induced Osteonecrosis of the Jaw in a Male Osteoporotic Patient.

    Calcif Tissue Int. 2014 May 8; Authors: Neuprez A, Rompen E, Crielaard JM, Reginster JY

    We report the first case of teriparatide adjuvant role in the management of a denosumab-induced osteonecrosis of the jaw in a... Lees meer

    Gepost op 11 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Critical impact of patient knowledge and bone density testing on starting osteoporosis treatment after fragility fracture: secondary analyses from two controlled trials.

    Osteoporos Int. 2014 May 7; Authors: Majumdar SR, McAlister FA, Johnson JA, Weir DL, Bellerose D, Hanley DA, Russell AS, Rowe BH 

    INTRODUCTION: In the year following fragility fracture, fewer than one quarter... Lees meer

    Gepost op 11 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing.

    Osteoporos Int. 2013 Oct;24(10):2659-70 Authors: Jeyabalan J, Viollet B, Smitham P, Ellis SA, Zaman G, Bardin C, Goodship A, Roux JP, Pierre M, Chenu C 

    INTRODUCTION: In view of the increased incidence of... Lees meer

    Gepost op 11 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Bone Mineral Density Changes Following Discontinuation of Ronacaleret Treatment: Off-treatment Extension of a Randomized, Dose-finding Phase II Trial.

    Bone. 2014 Apr 30; Authors: Fitzpatrick LA, Wooddell M, Dabrowski CE, Cicconetti G, Gordon DN 

    CONTEXT: Parathyroidectomy in patients with hyperparathyroidism can produce subsequent increases in bone mineral... Lees meer

    Gepost op 07 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Evaluation of the FRAX Model for Hip Fracture Predictions in the Population-based Kuopio Osteoporosis Risk Factor and Prevention Study (OSTPRE).

    Calcif Tissue Int. 2014 May 4; Authors: Sund R, Honkanen R, Johansson H, Odén A, McCloskey E, Kanis J, Kröger H

    Calibration of the Finnish FRAX model was evaluated using a locally derived... Lees meer

    Gepost op 07 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effect of supplemental vitamin D and calcium on serum sclerostin levels.

    Eur J Endocrinol. 2014 Apr;170(4):645-50 Authors: Dawson-Hughes B, Harris SS, Ceglia L, Palermo NJ 

    OBJECTIVE: Serum sclerostin levels have been reported to be inversely associated with serum 25OHD levels, but... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Vitamin D supplementation increases calcium absorption without a threshold effect.

    Am J Clin Nutr. 2014 Mar;99(3):624-31 Authors: Aloia JF, Dhaliwal R, Shieh A, Mikhail M, Fazzari M, Ragolia L, Abrams SA

    BACKGROUND: The maximal calcium absorption in response to vitamin D has been proposed as a... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Association Between Use of Antiepileptic Drugs and Fracture Risk: A Systematic Review and Meta-analysis.

    Bone. 2014 Apr 25; Authors: Shen C, Chen F, Zhang Y, Guo Y, Ding M

    BACKGROUND: It has been shown that antiepileptic drugs (AEDs) may have a detrimental effect on bone health and translate into an increased risk of... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prevalence of osteoporosis in men aged 65-75 in a primary care setting. A practice audit after application of the Canadian 2010 guidelines for osteoporosis screening.

    Clin Rheumatol. 2014 Apr 30; Authors: Ferrari R

    Current Canadian osteoporosis guidelines recommend routine bone density screening of men at age 65. The purpose of this study is to determine the prevalence of... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Practical guide to bone health in the spectrum of advanced prostate cancer.

    Can J Urol. 2014 Apr;21(2 Supp 1):84-92 Authors: Butoescu V, Tombal B

    INTRODUCTION: In the advanced stage of prostate cancer, bone is consistently the first and, later on, the dominant extra-nodal metastatic site.... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine.

     J Bone Miner Res. 2014 Apr 26; Authors: Wright NC, Looker AC, Saag KG, Curtis JR, Delzell ES, Randall S, Dawson-Hughes B

    The goal of our study was to estimate the prevalence of osteoporosis and low bone mass... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • AXT914 a novel, orally-active parathyroid hormone-releasing drug in two early studies of healthy volunteers and postmenopausal women.

    Bone. 2014 Apr 24; Authors: John MR, Harfst E, Loeffler J, Belleli R, Mason J, Bruin GJ, Seuwen K, Klickstein LB, Mindeholm L, Widler L, Kneissel M

    Antagonism of the calcium-sensing receptor in the parathyroid... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Handgrip Strength but not Appendicular Lean Mass is an Independent Predictor of Functional Outcome in Hip-Fracture Women: A Short-Term Prospective Study.

    Arch Phys Med Rehabil. 2014 Apr 21; Authors: Di Monaco M, Castiglioni C, De Toma E, Gardin L, Giordano S, Di Monaco R, Tappero R 

    OBJECTIVE: To investigate the contribution of muscle mass and handgrip strength... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prevalence of vitamin D inadequacy in European women aged over 80 years.

    Arch Gerontol Geriatr. 2014 Apr 5; Authors: Bruyère O, Slomian J, Beaudart C, Buckinx F, Cavalier E, Gillain S, Petermans J, Reginster JY

    Inadequate vitamin D status is associated with secondary... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Bone health in cancer patients: ESMO Clinical Practice Guidelines.

    Ann Oncol. 2014 Apr 29; Authors: Coleman R, Body JJ, Aapro M, Hadji P, Herrstedt J, on behalf of the ESMO Guidelines Working Group 

    There are three distinct areas of cancer management that make bone health in... Lees meer

    Gepost op 04 May 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Emerging multifunctional roles of Claudin tight junction proteins in bone.

    Endocrinology. 2014 Apr 23;:en20141173 Authors: Alshbool FZ, Mohan S

    The imbalance between bone formation and resorption during bone remodeling has been documented to be a major factor in the pathogenesis of... Lees meer

    Gepost op 25 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Calcium and Vitamin D in Sarcoidosis: Is Supplementation Safe?

    J Bone Miner Res. 2014 Apr 18; Authors: Kamphuis LS, Bonte-Mineur F, van Laar JA, van Hagen PM, van Daele PL

    Granulomas in sarcoidosis express high levels of 1α-hydroxylase, an enzyme that catalyzes the... Lees meer

    Gepost op 23 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • 7 Tesla MRI of bone microarchitecture discriminates between women without and with fragility fractures who do not differ by bone mineral density.

    J Bone Miner Metab. 2014 Apr 22; Authors: Chang G, Honig S, Liu Y, Chen C, Chu KK, Rajapakse CS, Egol K, Xia D, Saha PK, Regatte RR  

    Osteoporosis is a disease of poor bone quality. Bone mineral density (BMD)... Lees meer

    Gepost op 23 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Insights from the Global Longitudinal Study of Osteoporosis in Women (GLOW).

    Nat Rev Endocrinol. 2014 Apr 22; Authors: Watts NB

    GLOW is an observational, longitudinal, practice-based cohort study of osteoporosis in 60,393 women aged ≥55 years in 10 countries on three continents. In this... Lees meer

    Gepost op 23 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prenatal Calcium and Vitamin D Intake, and Bone Mass in Later Life.

    Curr Osteoporos Rep. 2014 Apr 17; Authors: Curtis EM, Moon RJ, Dennison EM, Harvey NC

    The aging population will result in an increasing burden of osteoporotic fractures, necessitating the identification of novel... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Rates of Non-vertebral Osteoporotic Fractures in Rheumatoid Arthritis and Postfracture Osteoporosis Care in a Period of Evolving Clinical Practice Guidelines.

    Calcif Tissue Int. 2014 Apr 16; Authors: Roussy JP, Bessette L, Bernatsky S, Rahme E, Lachaine J  

    In 2002, guidelines for the management of osteoporosis were published by Osteoporosis Canada and widely... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Associations between objectively-measured sedentary behaviour and physical activity with bone mineral density in adults and older adults, the NHANES study.

    Bone. 2014 Apr 12; Authors: Chastin SF, Mandrichenko O, Helbostadt JL, Skelton DA  

    BACKGROUND: Lack of physical activity (PA) is an important modifiable risk factor for bone mineral density (BMD). Time spent... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Obstructive Sleep Apnea and Risk of Osteoporosis: A Population-Based Cohort Study in Taiwan.

    J Clin Endocrinol Metab. 2014 Apr 15;:jc20141718 Authors: Chen YL, Weng SF, Shen YC, Chou CW, Yang CY, Wang JJ, Tien KJ 

    Background: Obstructive sleep apnea (OSA) is associated with metabolic, endocrine, and... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Proton pump inhibitor use and fracture risk - effect modification by histamine H1 receptor blockade. Observational case-control study using National Prescription Data.

    Bone. 2013 Nov;57(1):269-71 Authors: Abrahamsen B, Vestergaard P

    It remains unknown why proton pump inhibitor (PPI) use may be associated with risk of osteoporotic fractures; evidence of direct effects on calcium... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Added value of trabecular bone score to bone mineral density for prediction of osteoporotic fractures in postmenopausal women: the OPUS study.

    Bone. 2013 Nov;57(1):232-6 Authors: Briot K, Paternotte S, Kolta S, Eastell R, Reid DM, Felsenberg D, Glüer CC, Roux C 

    The objective of this study was to consider whether trabecular bone score (TBS)... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effectiveness of risedronate and alendronate on nonvertebral fractures: an observational study through 2 years of therapy.

    Osteoporos Int. 2013 Aug;24(8):2345-52 Authors: Lindsay R, Watts NB, Lange JL, Delmas PD, Silverman SL 

    INTRODUCTION: Post hoc analyses of the placebo-controlled trials suggested earlier effects for... Lees meer

    Gepost op 21 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The bone-fat interface: basic and clinical implications of marrow adiposity.

    Lancet Diabetes Endocrinol. 2014 Feb 19; Authors: Devlin MJ, Rosen CJ 

    Obesity and osteoporosis are two of the most common chronic disorders of the 21st century. Both are accompanied by significant morbidity.... Lees meer

    Gepost op 16 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men.

    Cochrane Database Syst Rev. 2014 Apr 14;4:CD000227 Authors: Avenell A, Mak JC, O'Connell D

    BACKGROUND: Vitamin D and related compounds have been used to prevent osteoporotic fractures in older people. This is... Lees meer

    Gepost op 16 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Osteoporosis drugs appear to impede cell membrane repair

    A class of drugs widely used to treat osteoporosis appears to impede a cell's ability to repair a protective outer membrane that helps determine what enters and exits, researchers report. The inability to quickly repair... Lees meer

    Gepost op 16 April 2014

    Bron: http://feeds.sciencedaily.c....

  • Capture the Fracture

    In April 2013, IOF officially launched the Capture the Fracture programme, a multi-stakeholder campaign to prevent secondary fractures due to osteoporosis through the implementation of Fracture Liaison Services (FLS)... Lees meer

    Gepost op 16 April 2014

    Bron: http://www.iofbonehealth.or....

  • Examining the impact of reimbursement on referral to bone density testing for older adults: 8 years of data from the Barwon Statistical Division, Australia.

    Arch Osteoporos. 2013;8(1-2):152 Authors: Brennan SL, Kotowicz MA, Sarah B, Leslie WD, Ebeling PR, Metge CJ, Dobbins AG, Pasco JA 

    INTRODUCTION: On April 1, 2007 Medicare Australia revised reimbursement... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Hyperkyphosis, Kyphosis Progression, and Risk of Non-Spine Fractures in Older Community Dwelling Women: The Study of Osteoporotic Fractures (SOF).

    J Bone Miner Res. 2014 Apr 9; Authors: Kado DM, Miller-Martinez D, Lui LY, Cawthon P, Katzman WB, Hillier TA, Fink HA, Ensrud KE

    While accentuated kyphosis is associated with osteoporosis, it is unknown whether it... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Inflammatory Markers and Risk of Hip Fracture in Older White Women: The Study of Osteoporotic Fractures.

    J Bone Miner Res. 2014 Apr 9; Authors: Barbour KE, Lui LY, Ensrud KE, Hillier TA, Leblanc ES, Ing SW, Hochberg MC, Cauley JA, for the Study of Osteoporotic Fractures (SOF) Research Group 

    Hip fractures are the... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Low Serum Thyrotropin Level and Duration of Suppression as a Predictor of Major Osteoporotic Fractures - The OPENTHYRO Register Cohort.

    J Bone Miner Res. 2014 Apr 9; Authors: Abrahamsen B, Jørgensen HL, Laulund AS, Nybo M, Brix TH, Hegedüs L

    BACKGROUND: The relationship between thyrotoxicosis and osteoporotic fractures remains... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus.

    BMC Endocr Disord. 2014 Apr 11;14(1):33 Authors: Leidig-Bruckner G, Grobholz S, Bruckner T, Scheidt-Nave C, Nawroth P, Schneider JG

    BACKGROUND: Increased risk of osteoporosis and its clinical significance in... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • U.S. adults meeting 2010 American College of Rheumatology criteria for treatment and prevention of glucocorticoid-induced osteoporosis.

    Arthritis Care Res (Hoboken). 2014 Apr 9; Authors: Overman RA, Toliver JC, Yeh JY, Gourlay ML, Deal CL

    Background/Purpose: The American College of Rheumatology (ACR) updated its guidelines on the prevention and... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • A service development study of the assessment and management of fracture risk in Parkinson's disease.

    J Neurol. 2014 Apr 10; Authors: Shribman S, Torsney KM, Noyce AJ, Giovannoni G, Fearnley J, Dobson R

    Parkinson's disease (PD) is associated with an increased risk of fragility fracture. FRAX and Qfracture are... Lees meer

    Gepost op 13 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Pharmacists Can Use FRAX to Identify Osteoporosis Risk

    The pharmacist can help prevent osteoporosis from occurring and, in those who already have the condition, help minimale risk for fracture, according to a presentation at the American Pharmacists Association (APhA) 2014... Lees meer

    Gepost op 13 April 2014

    Bron: http://news.google.com/news....

  • Trabecular Microfractures in the Femoral Head with Osteoporosis: Analysis of Microcallus Formations by Synchrotron Radiation Micro CT.

    Bone. 2014 Apr 2; Authors: Okazaki N, Chiba K, Taguchi K, Nango N, Kubota S, Ito M, Osaki M

    Trabecular bone microfracture pathogenesis and associated healing processes are not well understood. We analyzed the... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Incremental Predictive Value of Sarcopenia for Incident Fracture in an Elderly Chinese Cohort: Results From the Osteoporotic Fractures in Men (MrOs) Study.

     J Am Med Dir Assoc. 2014 Apr 2; Authors: Yu R, Leung J, Woo J 

    OBJECTIVES: We examined whether sarcopenia is predictive of incident fractures among older men, whether the inclusion of sarcopenia in... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Usefulness of bone density measurement in fallers.

    Joint Bone Spine. 2014 Apr 2; Authors: Blain H, Rolland Y, Beauchet O, Annweiler C, Benhamou CL, Benetos A, Berrut G, Audran M, Bendavid S, Bousson V, Briot K, Brazier M, Breuil V, Chapuis L, Chapurlat R, Cohen-Solal M,... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • There is still a care gap in osteoporosis management for patients with rheumatoid arthritis.

    Joint Bone Spine. 2014 Apr 2; Authors: Watt J, Thompson A, Le Riche N, Pope J 

    OBJECTIVES: To assess compliance rates with the current Canadian osteoporosis guidelines and whether the Fracture Risk Assessment... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Bone marrow fat.

    Joint Bone Spine. 2014 Apr 1; Authors: Hardouin P, Pansini V, Cortet B

    Bone marrow fat (BMF) results from an accumulation of fat cells within the bone marrow. Fat is not a simple filling tissue but is now... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • International and ethnic variability of falls in older men.

    Scand J Public Health. 2014 Mar;42(2):194-200 Authors: Karlsson MK, Ribom EL, Nilsson JÅ, Karlsson C, Cöster M, Vonschewelov T, Mallmin H, Ljunggren Ö, Ohlsson C, Mellström D, Lorentzon M, Leung PC, Lau... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Three New Reports of the IOF

    Providing evidence-based solutions Three groundbreaking new reports published by IOF in 2013 reveal the burden of osteoporosis in Europe and the Asia-Pacific. The reports are being used by national osteoporosis societies as... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.iofbonehealth.or....

  • Interaction between Muscle and Bone.

     J Bone Metab. 2014 Feb;21(1):29-40 Authors: Kaji H

    The clinical significance of sarcopenia and osteoporosis has increased with the increase in the population of older people. Sarcopenia is defined by... Lees meer

    Gepost op 09 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Long-term risk of medical conditions associated with breast cancer treatment.

    Breast Cancer Res Treat. 2014 Apr 3; Authors: Hill DA, Horick NK, Isaacs C, Domchek SM, Tomlinson GE, Lowery JT, Kinney AY, Berg JS, Edwards KL, Moorman PG, Plon SE, Strong LC, Ziogas A, Griffin CA, Kasten CH, Finkelstein... Lees meer

    Gepost op 06 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Declining rates of osteoporosis management following fragility fractures in the u.s., 2000 through 2009.

     J Bone Joint Surg Am. 2014 Apr 2;96(7):e52 Authors: Balasubramanian A, Tosi LL, Lane JM, Dirschl DR, Ho PR, O'Malley CD  

    Clinical practice recommendations state that patients with fragility... Lees meer

    Gepost op 06 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The global burden attributable to low bone mineral density.

    Ann Rheum Dis. 2014 Apr 1; Authors: Sànchez-Riera L, Carnahan E, Vos T, Veerman L, Norman R, Lim SS, Hoy D, Smith E, Wilson N, Nolla JM, Chen JS, Macara M, Kamalaraj N, Li Y, Kok C, Santos-Hernández C, March... Lees meer

    Gepost op 06 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effects of up to 5 Years of Denosumab Treatment on Bone Histology and Histomorphometry: The FREEDOM Study Extension.

    J Bone Miner Res. 2014 Apr 1; Authors: Brown JP, Reid IR, Wagman RB, Kendler D, Miller PD, Jensen JE, Bolognese MA, Daizadeh N, Valter I, Zerbini CA, Dempster DW

    Denosumab reduced bone resorption, increased BMD,... Lees meer

    Gepost op 06 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Economic evaluation of an osteoporosis screening campaign using FRAX

    In new research presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases today, investigators showed that an osteoporosis screening strategy using FRAX as a pre-screening tool is... Lees meer

    Gepost op 06 April 2014

    Bron: http://news.google.com/news....

  • New FRAX app launched by the International Osteoporosis Foundation

    Osteoporosis management guidelines around the world now recommend that fracture risk assessment be part of any clinical evaluation for osteoporosis. As a result, rather than relying on bone mineral density values alone,... Lees meer

    Gepost op 06 April 2014

    Bron: http://news.google.com/news....

  • EMAS position statement: The management of postmenopausal women with vertebral osteoporotic fracture.

    Maturitas. 2014 Mar 7; Authors: Triantafyllopoulos IK, Lambropoulou-Adamidou K, Nacopoulos CC, Papaioannou NA, Ceausu I, Depypere H, Erel CT, Pérez-López FR, Schenck-Gustafsson K, van der Schouw YT, Simoncini... Lees meer

    Gepost op 02 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • TBS result is not affected by lumbar spine osteoarthritis.

    Osteoporos Int. 2014 Apr 1; Authors: Kolta S, Briot K, Fechtenbaum J, Paternotte S, Armbrecht G, Felsenberg D, Glüer CC, Eastell R, Roux C .

    INTRODUCTION: Lumbar... Lees meer

    Gepost op 02 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Patterns and predictors of osteoporosis medication discontinuation and switching among Medicare beneficiaries.

    BMC Musculoskelet Disord. 2014 Apr 1;15(1):112 Authors: Yun H, Curtis JR, Guo L, Kilgore M, Muntner P, Saag K, Matthews R, Morrisey M, Wright NC, Becker DJ, Delzell E 

    BACKGROUND: Low adherence to... Lees meer

    Gepost op 02 April 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Meta-analysis of risk factors for the second hip fracture (SHF) in elderly patients.

    Arch Gerontol Geriatr. 2014 Mar 20; Authors: Zhu Y, Chen W, Sun T, Zhang Q, Cheng J, Zhang Y

    This study aims to quantitatively summarize the risk factors for the incidence of SHF. A meta-analysis was performed with... Lees meer

    Gepost op 30 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • NCCN Task Force Report: Bone Health In Cancer Care.

    J Natl Compr Canc Netw. 2013 Aug;11 Suppl 3:S1-50; quiz S51 Authors: Gralow JR, Biermann JS, Farooki A, Fornier MN, Gagel RF, Kumar R, Litsas G, McKay R, Podoloff DA, Srinivas S, Van Poznak CH

    Bone health and... Lees meer

    Gepost op 30 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Alendronate-induced atypical bone fracture: evidence that the drug inhibits osteogenesis.

    J Clin Pharm Ther. 2014 Mar 24; Authors: Patntirapong S, Singhatanadgit W, Arphavasin S

    OBJECTIVE: Alendronate (ALN) is used for the treatment of post-menopausal osteoporosis. By reducing bone turnover, it... Lees meer

    Gepost op 30 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Predictors of Excess Mortality Following Fracture: A Population-Based Cohort Study.

    J Bone Miner Res. 2014 Feb 12; Authors: Melton LJ, Atkinson EJ, St Sauver JL, Achenbach SJ, Therneau TM, Rocca WA, Amin S

    To determine the extent to which excess mortality following fractures due to particular... Lees meer

    Gepost op 30 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Impacts of Body Mass Index, Physical Activity, and Smoking on Femoral Bone Loss. The Tromsø Study.

    J Bone Miner Res. 2014 Mar 28; Authors: Emaus N, Wilsgaard T, Ahmed LA

    Bone mineral density (BMD) is a reflection of bone strength and lifestyles that preserve bone mass may reduce fracture risk in old age. This... Lees meer

    Gepost op 30 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Age discrimination in osteoporosis screening—Data from the Aalborg University Hospital Record for Osteoporosis Risk Assessment (AURORA)

    We report data from the 8,131 consecutive evaluations in 7914 individuals at the Osteoporosis Clinic from January 1st 2010 through December 31st 2012.Results: Risk factor data were available in >96% and DXA in 98%.... Lees meer

    Gepost op 30 March 2014

    Bron: http://www.medworm.com/inde....

  • Melk drinken tijdens tienerjaren helpt niet om osteoporose te voorkomen

    Vaak wordt aangeraden om tijdens de kinder- en tienerjaren veel melk te drinken, om op die manier voldoende botmassa op te bouwen en op latere leeftijd botontkalking (osteoporose) te voorkomen. Een nieuw Amerikaans onderzoek... Lees meer

    Gepost op 30 March 2014

    Bron: http://news.google.com/news....

  • OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study.

    Bone. 2013 Oct;56(2):474-81 Authors: LaCroix AZ, Jackson RD, Aragaki A, Kooperberg C, Cauley JA, Chen Z, Leboff MS, Duggan D, Wactawski-Wende J

    PURPOSE: The osteoprotogerin/receptor activator of NF-kappa... Lees meer

    Gepost op 25 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Use of strontium ranelate and risk of acute coronary syndrome: cohort study.

    Ann Rheum Dis. 2014 Mar 20; Authors: Svanström H, Pasternak B, Hviid A

    BACKGROUND: A recent pooled analysis of randomised trials found an increased risk of myocardial infarction with use of the... Lees meer

    Gepost op 25 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Early Changes in Bone Density, Micro-Architecture, Bone Resorption and Inflammation Predict the Clinical Outcome 12 Weeks After Conservatively Treated Distal Radius Fractures: An Exploratory Study.

    Fracture healing is an active process with early changes in bone and inflammation. We performed an exploratory study evaluating the association between early changes in densitometric, structural, biomechanical and... Lees meer

    Gepost op 22 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Effects of Odanacatib on the Radius and Tibia of Postmenopausal Women: Improvements in Bone Geometry, Microarchitecture and Estimated Bone Strength.

    The cathepsin K inhibitor odanacatib, currently in phase 3 development for postmenopausal osteoporosis, has a novel mechanism of action that reduces bone resorption while maintaining bone formation. In phase 2 studies,... Lees meer

    Gepost op 22 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Biochemical Markers of Bone Turnover in Chronic Obstructive Pulmonary Disease (COPD).

    Osteoporosis has a higher prevalence in COPD patients and its etiology is very complex, it has been linked with reduced physical activity, low body mass index (BMD), a worse degree of airflow limitation and... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The effects of bazedoxifene in the ovariectomized aged cynomolgus monkey.

    Bazedoxifene (BZA) is a novel selective estrogen receptor modulator in clinical development for the prevention and treatment of postmenopausal osteoporosis. This preclinical study evaluated the efficacy and safety of BZA in... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Evaluation of the anti-osteoporotic effects of metformin and sitagliptin in postmenopausal diabetic women.

    Osteoporosis is the most important metabolic bone disease in patients with diabetes mellitus. Several studies have documented that metformin is osteogenic in vitro. In contrast, others showed no effect of metformin on the... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Interrelationship among muscle, fat, and bone: Connecting the dots on cellular, hormonal, and whole body levels.

    While sarcopenia and sarcopenic obesity have been recognized in the last decade, a combined concept to include decreased muscle mass and strength, as well as decreased bone mass with coexistence of adiposity is discussed... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The association between plasma homocysteine levels and bone quality and bone mineral density parameters in older persons.

    INTRODUCTION: High plasma homocysteine levels have been associated with incident osteoporotic fractures, but the mechanisms underlying this association are still unknown. It has been hypothesized that homocysteine might... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Clinical treatment outcomes for 40 patients with bisphosphonates-related osteonecrosis of the jaws.

    BACKGROUND/PURPOSE: Bisphosphonates (BPs) are used to treat osteoporosis and bone metastases from malignancy. They may result in BPs-related osteonecrosis of the jaws (BRONJ) in a subset of patients receiving BPs. This study... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Serum periostin is associated with fracture risk in postmenopausal women: a 7 years prospective analysis of the OFELY study.

    Purpose: Periostin (POSTN) is a secreted gamma-carboxyglutamic acid-containing protein (Gla protein) expressed mainly in the periosteum in adult individuals. POSNT deficient mice develop periodontis and osteoporosis with... Lees meer

    Gepost op 19 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • National Bone Health Alliance Clinical Diagnosis of Osteoporosis Working ...

    The National Bone Health Alliance (NBHA) Clinical Diagnosis of Osteoporosis Working Group recommends expanding the criteria for making a diagnosis of osteoporosis to include all post-menopausal women and all men age 50 en... Lees meer

    Gepost op 19 March 2014

    Bron: http://news.google.com/news....

  • Bone mass behavior after 1 year of different treatment strategies in prostate cancer patients subjected to androgen deprivation therapy.

    The aim of this study was to evaluate bone mass changes after 1 year of four different types of pharmacological intervention. Ninety-seven prostate cancer patients treated with androgen deprivation therapy, and severe... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Choice of Lumbar Spine Bone Density Reference Database for Fracture Prediction in Men and Women: A Population-Based Analysis.

    The diagnosis of osteoporosis in men is controversial, although most studies demonstrate similar fracture rates for men and women with the same level of hip bone mineral density (BMD). Whether this applies to the lumbar... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Fracture incidence after 3 years of aromatase inhibitor therapy.

    BACKGROUND: The purpose of this study was to describe the fracture incidence and bone mineral density (BMD) evolution in a large cohort of post-menopausal women with breast cancer after 3 years of aromatase inhibitor (AI)... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Mortality following the first hip fracture in Norwegian women and men 1999-2008. A NOREPOS study.

    Hip fractures are associated with increased mortality and their incidence in Norway is one of the highest worldwide. The aim of this nationwide study was to examine short and long term mortality after hip fractures, burden... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Anti-osteoporotic drugs and vascular calcification: the bidirectional calcium traffic.

    During the last years, numerous epidemiological studies have demonstrated a direct relationship between vascular calcification and low bone mineral density. This observation is in line with experimental data demonstrating... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Plasma level of homocysteine associated with severe vertebral fracture in postmenopausal women.

    The aim of this cross-sectional cohort study was to clarify risk factors for severe vertebral fractures in postmenopausal Japanese women. Subjects were ambulatory volunteers age over 50 years who were recruited from a... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Overlapping and Continued Alendronate or Raloxifene Administration in Patients on Teriparatide: Effects on Areal and Volumetric Bone Mineral Density The CONFORS Study.

    Nine month teriparatide (TPTD) monotherapy followed by co-administration of raloxifene (RAL) or alendronate (ALN) for another nine months resulted in incremental bone mineral density (BMD) increase. The aim of this study was... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • FRAX without Bone Mineral Density Versus Osteoporosis Self-Assessment Screening Tool as Predictors of Osteoporosis in Primary Screening of Individuals Aged 70 and Older.

    To compare two well-validated tools-the FRAX without bone mineral density (BMD) and the Osteoporosis Self-Assessment Screening Tool (OST)-in predicting osteoporosis and to define thresholds above and below which it would be... Lees meer

    Gepost op 16 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Sclerostin and bone strength in women in their 10th decade of life.

    Sclerostin is a potent inhibitor of bone formation but has been shown to correlate positively with areal bone mineral density (aBMD). Little is known about its relationship to parameters of bone strength and volumetric BMD... Lees meer

    Gepost op 09 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Sharper view gained of osteoporosis development: Intracellular protein discovered

    In the bones supporting our bodies, calcium regulation occurs by balancing the activities of osteoclasts, which are groups of cells that increase the calcium concentration in blood by destroying bone tissue, and osteoblasts,... Lees meer

    Gepost op 09 March 2014

    Bron: http://feeds.sciencedaily.c....

  • Predicting fracture risk for treated, untreated patients

    A new study summarizes the clinical performance of serum procollagen type I N propeptide and serum C-terminal cross-linking telopeptide of type I collagen in fracture risk prediction in untreated individuals in prospective... Lees meer

    Gepost op 09 March 2014

    Bron: http://feeds.sciencedaily.c....

  • PINP as a biological response marker during teriparatide treatment for osteoporosis.

    Postmenopausal women with severe osteoporosis may require treatment with the bone anabolic drug teriparatide. While changes in bone mineral density (BMD) are one measure of response, BMD changes often require a minimum of... Lees meer

    Gepost op 09 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Prevalence of vertebral fractures and minor vertebral deformities evaluated by DXA-assisted vertebral fracture assessment (VFA) in a population-based study of postmenopausal women: the FRODOS study.

     Population-based studies performed with vertebral fracture assessment (VFA) morphometric technology are lacking in postmenopausal osteoporosis. In this study, we show a lower than expected prevalence of vertebral... Lees meer

    Gepost op 09 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • The spectrum of fractures in the elderly.

    Fractures in patients aged ≥ 65 years constitute an increasing burden on health and social care and are associated with a high morbidity and mortality. There is little accurate information about the epidemiology of... Lees meer

    Gepost op 05 March 2014

    Bron: http://www.ncbi.nlm.nih.gov....

  • Delayed/non‐union of upper limb fractures with bisphosphonates: systematic review and recommendations

    Differences in union time between BP users and non‐users are not significant enough to change current practice patterns and do not outweigh the benefits of BP therapy. There is no evidence to encourage early surgical... Lees meer

    Gepost op 02 March 2014

    Bron: http://www.medworm.com/inde....

  • Two Years of Denosumab and Teriparatide Administration in Postmenopausal Women with Osteoporosis (The DATA Extension Study): a Randomized Controlled Trial

    Two years of concomitant teriparatide and denosumab therapy increases BMD more than either medication alone and more than has been reported with any current therapy. The combination of these agents may prove to be an... Lees meer

    Gepost op 02 March 2014

    Bron: http://www.medworm.com/inde....

  • Antidepressant use and 10-year incident fracture risk: the population-based Canadian Multicentre Osteoporosis Study (CaMoS)

    We used data from a large, prospective Canadian cohort to assess the association between selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs) and fracture. We found an... Lees meer

    Gepost op 02 March 2014

    Bron: http://www.medworm.com/inde....

  • Osteoporosis Screening Strategies for Younger Postmenopausal WomenOsteoporosis Screening Strategies for Younger Postmenopausal Women

    None of the three common osteoporosis screening strategies is optimal for younger postmenopausal women, and the US Preventive Services Task Force (USPSTF) strategy is the worst. 

    Lees meer

    Gepost op 02 March 2014

    Bron: http://www.medworm.com/inde....

  • Fracture liaison service: impact on subsequent nonvertebral fracture incidence and mortality.

    CONCLUSIONS: Patients seen at the fracture liaison service had a significantly lower mortality and subsequently a lower risk of nonvertebral fracture than those not seen at the fracture liaison service, with a reduction of... Lees meer

    Gepost op 02 March 2014

    Bron: http://www.medworm.com/inde....

  • Rates of osteoporosis treatment after hip fracture on the decline

    The majority of patients with hip fracture do not receive osteoporosis treatment and the rates of treatment have been declining, a finding that is not consistent with osteoporosis treatment guidelines endorsed by the... Lees meer

    Gepost op 02 March 2014

    Bron: http://news.google.com/news....

  • Conventional assessment strategies identify more postmenopausal women with ...

    The U.S. Preventative Service Task Force recommendation of osteoporosis screening for women younger than 65 years was moderately better than chance alone, but inferior to conventional strategies, according to results of a... Lees meer

    Gepost op 05 February 2014

    Bron: http://news.google.com/news....

  • Patient Perceptions of Osteoporosis Treatment Thresholds.

    There is substantial variability in preferences for postmenopausal osteoporosis treatment. Presentation of individualized fracture risks as recommended by current guidelines has potential to allow better targeting to... Lees meer

    Gepost op 01 February 2014

    Bron: http://www.medworm.com/inde....

  • Osteoporosis/Osteopenia Prevalent in Chronic Pancreatitis

    Sixty-five percent of patients with chronic pancreatitis have osteoporosis or osteopenia, according to a meta-analysis published in the February issue of Clinical Gastroenterology and Hepatology.  »

    Lees meer

    Gepost op 31 January 2014

    Bron: http://news.google.com/news....

  • Finding could lead to new treatments for osteoporosis

    Scientists at Washington University School of Medicine in St. Louis have discovered what appears to be a potent stimulator of new bone growth. The finding could lead to new treatments for osteoporosis and other diseases that... Lees meer

    Gepost op 31 January 2014

    Bron: http://news.google.com/news....

  • Osteoporosis screening recommendations may miss two-thirds of women aged

    Using health data on women ages 50–64 from the Women's Health Initiative study, the researchers found that the current strategy would identify only 34 percent of women who actually had bone-mineral density in the... Lees meer

    Gepost op 30 January 2014

    Bron: http://news.google.com/news....

  • Scientists develop automated system that identifies high-risk osteoporosis ...

    An automated system that identifies high-risk osteoporosis patients being treated for fractures and can generate letters encouraging follow-up is an effective way to promote osteoporosis intervention and prevent future... Lees meer

    Gepost op 29 January 2014

    Bron: http://news.google.com/news....

  • Study Provides Guidance On Drug Holidays

    Doctors commonly recommend drug holidays, or breaks, from certain osteoporosis drugs due to the risks associated with these treatments. Yet little has been known about the ideal duration of... Lees meer

    Gepost op 15 January 2014

    Bron: http://news.google.com/news....

  • Changes in Bone Mineral Density After Parathyroidectomy in Elderly Patients With Primary Hyperparathyroidism

    In the United States, approximately 1.5 million fractures occur due to osteoporosis annually; over 1/3 are due to low-impact falls among the community-dwelling elderly. Primary hyperparathyroidism (pHPT), by increasing... Lees meer

    Gepost op 11 January 2014

    Bron: http://www.medworm.com/inde....

  • Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis

    Continuing widespread use of vitamin D for osteoporosis prevention in community-dwelling adults without specific risk factors for vitamin D deficiency seems to be inappropriate. (Source: LANCET)

    Lees meer

    Gepost op 11 January 2014

    Bron: http://www.medworm.com/inde....

  • EU Panel Recommends Suspension of Protelos/Osseor

    After an in-depth analysis, the European Medicines Agency's Pharmacovigilance Risk Assessment Committee determined that the drug's risks outweigh its benefits for treating osteoporosis. 

    Lees meer

    Gepost op 10 January 2014

    Bron: http://www.medworm.com/inde....

  • Rheumatoid arthritis and incident fracture in women: a case-control study

    Given that women with RA have a greater risk of fracture compared to women without RA, these patients may be a suitable target population for anti-resorptive agents; however, larger studies are warranted. (Source: BMC... Lees meer

    Gepost op 09 January 2014

    Bron: http://www.medworm.com/inde....

  • New Osteoporosis Drug Could Change Treatment

    Drug Could Change Treatment

    The experimental drug, romosozumab, frees the body's ability to stimulate bone production by blocking biochemical signals that naturally inhibit bone formation, explained Dr. Michael... Lees meer

    Gepost op 03 January 2014

    Bron: http://news.google.com/news....

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